CDX2 and neoplasm: CDX2 status (P = 0·018), WHO grade (P = 0·002), tumour budding (P < 0·001), PDC grade (P < 0·001), LVI (P < 0·001), PNI (P < 0·001), EMVI (P < 0·001), type of margin (P = 0·001) and pT category (P = 0·006) were associated with LNM in univariable analysis (Table 3).