GPT and neoplasm: Indications for systemic chemotherapy:Clinical or histopathological diagnosis confirmedMetastatic or recurrent tumour con be confirmed by imagingPS 0–2Peripheral blood neutrophil count > 1500/mm3; platelet count > 100 000/mm3Total bilirubin < 2.0 mg/dl; AST/ALT < 100 units/lSerum creatinine concentration no higher than upper limit of normal rangeWritten informed consent providedPatient has no serious complications