SCD and hyperinsulinemic hypoglycemia, familial, 4: Rictor deficiency results in reduced lipogenesis, which is not only due to decreased glucose uptake (discussed above) but also due to decreased expression of genes encoding lipogenic enzymes, such as acetyl-CoA carboxylase (ACC), ATP-citrate lyase (ACL), fatty acid synthase (FAS), and stearoyl-CoA desaturase (SCD1) [58, 61, 63, 74].