Furthermore, we also investigated the prognostic values of ApoA-I level in certain types of cancers and found that the pretreatment of ApoA-I level could act as a prognostic indicator in NPC (HR = 0.63, 95% CI: 0.54–0.73), CRC (HR = 0.48, 95% CI: 0.19–0.76), and HCC (HR = 0.46, 95% CI: 0.27–0.65). Here, APOA1 is linked to colorectal carcinoma.