EPAS1, RYR1, DSG2 (Desomgelin2) are related to cardiomyopathy and PTPRJ (Receptor-type tyrosine-protein phosphatase eta), FUT1 (fucosyltransferase1), HEG1 (heart development protein with EGF-like domains 1), PTPRZ1 (tyrosine phosphatase receptor-type Z polypeptide 1), SIGLEC1 (Sialic acid-binding Ig-like lectin 1 sialoadhesin), NPC1L1 (Niemann-Pick disease-type C1 gene-like 1), and NES (Nestin) are connected with the cardiovascular system, whereas DSG3 is important in maintaining the normal structure and function of hairs (Song et al., 2016). The gene discussed is NPC1L1; the disease is cardiomyopathy.