EPAS1 and cardiomyopathy: EPAS1, RYR1, DSG2 (Desomgelin2) are related to cardiomyopathy and PTPRJ (Receptor-type tyrosine-protein phosphatase eta), FUT1 (fucosyltransferase1), HEG1 (heart development protein with EGF-like domains 1), PTPRZ1 (tyrosine phosphatase receptor-type Z polypeptide 1), SIGLEC1 (Sialic acid-binding Ig-like lectin 1 sialoadhesin), NPC1L1 (Niemann-Pick disease-type C1 gene-like 1), and NES (Nestin) are connected with the cardiovascular system, whereas DSG3 is important in maintaining the normal structure and function of hairs (Song et al., 2016).