Methylation differences between BPD and HC subjects comprised a total of 256 significantly hypermethylated CpG sites in BPD, but significance of any of each didn't persist post Bonferroni correction. By selected quantitative analysis, hypermethylation in BPD was significant at particular CpG sites respecting APBA2, APBA3, KCNQ1, MCF2, NINJ2, GATA4 compared with HC subjects (GATA4 was significantly increased only in the bead chip assay). The gene discussed is GATA4; the disease is Borderline personality disorder.