Subjects: female outpatients with BPD (n = 281) without current episode of any axis I disorder. Diagnostics: DSM-IV, SCID-II, DIP-R, CTQ-SF. Methods: DNA bisulfite treatment, PCR amplification and pyrosequencing for selected methylation analysis of NR3C1 exon 1F (8 CpG sites). Here, NR3C1 is linked to Borderline personality disorder.