NR3C1 and Borderline personality disorder: Subjects with BPD, even without CT, showed higher NR3C1 methylation levels than MDD subjects with the same reported CT. In BPD, childhood SA, PN, and number of types of CT were significantly associated with increased NR3C1 methylation. No significant association was found between methylation status and childhood PA, EA and EN. In the whole sample, SA, PA, PN, EA, and EN were significantly associated with NR3C1 methylation. Number of types of CT was significant positively correlated with overall methylation level.