COMT and Borderline personality disorder: Dammann et al. (26) analyzed five neuropsychiatric genes assumed to be of significance for psychopathological phenotype, in particular genes coding for soluble catechol-O-methyltransferase (s-COMT), serotonin receptor 2A (HTR2A), NR3C1, and X-chromosomal MAOA and MAOB. Methylation levels of each gene promoter were quantified in PBC DNA of individuals with BPD (n = 26, 24 female) and in healthy controls (n = 11, all female).