Overall methylation of NR3C1 was significantly positively correlated with CT (in particular PA) and with clinical severity of BPD (in particular DIB-R total score and previous hospitalizations). No significant association between NR3C1 methylation level and general severity of CT. Methylation of individual CpG sites showed single significance for association with PA and EN (CpG1-3) and with EA (CpG6). This evidence concerns the gene NR3C1 and Borderline personality disorder.