SLC6A4 and Borderline personality disorder: According to previous data, these gene targeted studies confirmed the relevance of the serotonergic system for affective regulation and revealed methylation aberrances of the serotonin transporter (SLC6A4) and receptor genes (5HTR1B, 5HTR2A, and 5HTR3A) to be linked with antisocial traits (30, 31) and BPD (25, 26).