EGFR and neoplasm: In addition to greatly enhanced cytotoxicity and significant tumor growth inhibition, as well as prolonged tumor retention of radioactivity, which were anticipated from previous studies (Rosenkranz et al., 2017; Slastnikova et al., 2017a,b), 111In-labeled EGFR-targeted MNTs are demonstrated to possess promising for clinical translation pharmacokinetic profile.