Consistently, we detected a trend toward higher levels of MCP-3, which attracts and activates eosinophils39, in the BM of Early-MM mice when compared to Late-MM (Early-MM 376.9 ± 128.5 pg/mL (mean ± SE; n = 7); Late-MM 100.2 ± 15.45 pg/mL (n = 5); WT 169.8 ± 46.7 (n = 5); Supplementary Fig. 9). This evidence concerns the gene CCL7 and Miyoshi myopathy.