MYC and Miyoshi myopathy: Additionally, disease progression (i.e., M-spike ≥ 6%, which is characteristic of symptomatic, Late-MM; see ref. 33) was delayed in Vk*MYC IL-17KO mice (Fig. 2b) when compared to Vk*MYC IL-17WT mice, thus demonstrating that IL-17 is also a precocious propeller of MM in this model.