We next assessed if the four genes (CCDC71L, PRKAR2B, ADAMTS9, LOXL4) identified through colocalization of cIMT/carotid plaque with tissue-specific eQTLs also showed evidence for colocalization with CHD and stroke traits (Supplementary Data 1 and Supplementary Figure 6). The gene discussed is LOXL4; the disease is stroke disorder.