HAND2 and non-small cell lung carcinoma: Transwell migration and invasion assay results showed that, compared with control cells (C) and negative control cells (NC), overexpression of lncRNA HAND2-AS1 significantly inhibited, while treatment with exogenous TGF-β1 at a dose of 10 ng/ ml (Sigma-Aldrich) significantly promoted the migration (Figure 4A, P<0.05) and invasion (Figure 4B, P<0.05) of cells of NSCLC cell lines H1581 and H1993.