Considering the pharmacogenetic significance of NAT2 gene in view, previously several studies [14–25] have tried to establish a possible link between NAT2 481C>T, 590G>A, and 857G>A gene variants and the development of INH-induced hepatotoxicity in TB patients from different populations but failed to give concrete conclusion possibly due to small size, and still the said relationship is controversial. The gene discussed is NAT2; the disease is tuberculosis.