In our previous study, we compared the mouse ovarian cancer cell lines ID8 and ID8-KRAS (oncogenic KRAS (G12 V) transduced in the ID8 cell line) and observed that KRAS promoted rapid tumor formation with severe inflammation in vivo mouse models, although in vitro, ID8 cell proliferation was not affected by KRAS [15]. The gene discussed is KRAS; the disease is ovarian cancer.