ALB is used as a marker of nutritional status because of its association with the degree of malnutrition.[29] More importantly, a decrease of ALB level was observed in the cirrhosis patients, which is in line with our results.[30] Therefore, increases in ALT, AST, and TBIL levels as well as the decrease in ALB level play significant roles in cirrhosis, with the levels of both ALT and AST are associated with the severity of cirrhosis. This evidence concerns the gene ALB and Cirrhosis.