NRG1 and schizophrenia: Thousands of loci on the genome have been identified to be associated with schizophrenia (Allen et al., 2008), e.g. ANK3, ZNF804A, CACNA1C, NRG1, TCF4, and MHC region, etc (O’Donovan et al., 2008; Ripke et al., 2013; Schwab and Wildenauer, 2013).