Moreover, the in situ PCR detection of HR-HPVE6E7 genes and p16-INK4A overexpression in PCa tissues similar to that in human prostate epithelial cell lines (Ko et al., 2003; Theodore et al., 2010) and a male case of urothelial carcinoma with squamous differentiation associated withHPV in another report (Guma et al., 2016) are suggestive of early and late ongoing oncogenic processes in BHP and PCa, respectively. Here, CDKN2A is linked to posterior cortical atrophy.