A previous report from our Nigerian African population including 57 sporadic PD patients and 51 healthy controls did not identify LRRK2 p.G2019S mutations in either PD cases or controls.[7] In this study we aimed at exploring a larger cohort of PD cases and healthy controls from a Black African Nigerian background for the LRRK2 p.G2019S mutation to further clarify the role of this mutation in PD in sub-Saharan Africans. This evidence concerns the gene LRRK2 and Parkinson disease.