CD34 and breast ductal adenocarcinoma: To investigate whether SOX4 expression is also associated with increased angiogenesis in patients with human breast cancer, we examined CD34 expression (a marker for small and newly formed blood vessels) in 17 SOX4-low (SOX4LO) and 17 SOX4-high (SOX4HI) ductal carcinomas from our cohort (Figure 7F).