For a limited number of tumor types, downstream targets of SOX4 have been identified that were important for invasion such as NRP1 and SEMA3C (hepatocellular carcinoma; Liao et al., 2008), TEAD2 and RBP1 (lung cancer; Castillo et al., 2012) and EGFR, Tenascin C (prostate cancer; Scharer et al., 2009). The gene discussed is SOX4; the disease is neoplasm.