Dallol et al discovered that RASSF1A overexpression inhibits cell migration and changes cell morphology in the A549 lung cancer cell line.35 Duboiset et al reported that RASSF1A knockdown causes invasiveness, while restoring RASSF1A expression decreased A549 cell invasion in vitro.8 The results of our study were consistent with those of previous reports and verified the tumour‐suppressive effect of RASSF1A in lung cancer pathogenesis. This evidence concerns the gene RASSF1 and neoplasm.