The JAK‐STAT signalling (Janus kinase‐Signal transducer and activator of transcription proteins) is proved to involve in the process of immunity, development and human cancers.5 When JAK‐STAT signalling is activated, the ligands cause the dimerization of receptors, trans‐phosphorylation effect on JAK and subsequently promote STATs phosphorylation. The gene discussed is SOAT1; the disease is cancer.