Comparing diffuse astrocytomas of WHO grade II–IV with pilocytic astrocytomas, both pan‐M/M markers Iba1 and CD68 as well as the presumed M2‐marker C163 were found in significantly higher levels in pilocytic astrocytomas WHO grade I (Figure 2B, Table 1). The gene discussed is AIF1; the disease is diffuse astrocytoma.