Despite the locoregional heterogeneity, we found a significant positive association of the amounts of CD68‐, CD163‐ and CD206‐positive GAM subpopulations in the vital tumor core with prolonged overall survival of IDH1R132H‐non‐mutant GBM patients performing a median split for each M/M marker (Figure 3B). This evidence concerns the gene CD163 and neoplasm.