Recent investigations have also indicated that LOXL2 is a predictor of poor prognosis in specific tumour types, such as larynx squamous cell carcinomas and is associated with metastatic dissemination in basal breast carcinomas.28, 30 Therefore, we may conclude that LOXL2‐c is a good predictor of a poor prognosis in HCC patients. The gene discussed is LOXL2; the disease is laryngeal squamous cell carcinoma.