TWIST1 and hepatocellular carcinoma: As shown in a previous study, EMT regulators and VM are correlated, and many EMT regulators, such as Twist and Slug, can promote VM.14, 33, 41 Similarly, in the present study, we found that in another EMT regulator, the expression of SNAIL correlates with VM in HCC, and SNAIL itself exerts a positive effect on cell migration and invasion and capillary tube formation.