Vasculogenic mimicry has increasingly been considered to function simultaneously with angiogenesis.9, 37 A recent study revealed that LOXL2 regulates capillary formation and is required for tumour angiogenesis.25, 26 Consistently, in our study, we have reported that LOXL2 promotes VM in HCC. The gene discussed is LOXL2; the disease is hepatocellular carcinoma.