CD40LG and tuberculosis: To investigate mycobacteria‐specific antibody levels across ages, and to examine potential effects of HCMV co‐infection on antibody levels, this study tested 2187 stored serum samples (of which 27 were active TB cases) from a rural Ugandan cohort for IgG responses to Ag85A, purified protein derivative (PPD), lipoarabinomannan (LAM) and CFP10/ESAT6, along with IgM responses to Ag85A.