In discord with more than twenty studies conducted in Europe [6, 8, 12-14, 17, 27, 28], Eastern Asia [10, 11, 15, 16, 19], Colombia [18], Tunisia [26], and Egypt [30, 31], the minor T allele of STAT4 rs7574865 was not associated with RA in Syria (p>.05) as well as in Turkish [21], Iranian [29], and African American [20] populations. Here, STAT4 is linked to rheumatoid arthritis.