STAT4 and rheumatoid arthritis: The Minor Allele Frequency (MAF) of STAT4 rs7574865 among RA patients in Syria (25.3%) seems consistent with Tunisians (25%) [26] and Europeans (24%-30%) [6, 8, 12-14, 17, 27, 28] but higher than African Americans (15%) [20] and lower than Iranians (50%) [29], Eastern Asians (35%-42%) [11, 15, 16, 19], and Colombians (38%) [18].