Fgf10 mRNA is present in the osteoprogenitors in the frontal bone condensation (Veistinen et al., 2009), and genetic knock-down of Fgf10 rescues the skeletal phenotype in an Apert syndrome mouse model FgfR2-IIIc+/Δ (Hajihosseini et al., 2009). This evidence concerns the gene FGFR2 and Apert syndrome.