CCL2 and mental disorder: As shown in Fig. 1A, ANCOVA revealed a significant association of ‘mental disorder status’ with mRNA levels of IL-1β (F1,47 = 10.885, P = 0.002), IL-6 (F1,47 = 12.004, P = 0.001), CCL2 (F1,47 = 7.802, P = 0.008), CSF3 (F1,47 = 4.518, P = 0.039) and PLAUR (F1,47 = 13.423, P = 0.001) in the VAT, and mRNA levels of IL-6 (F1,47 = 6.046, P = 0.018) in the SAT.