In further support of a role for FOXM1 in neuroblastoma, Zha et al. reported high MEIS2 levels which is a transcription activator of the MuvB-BMYB-FOXM1 complex with FOXM1 being a direct target gene of MEIS2 and required for MEIS2 to upregulate mitotic genes51. The gene discussed is MEIS2; the disease is neuroblastoma.