CD8A and neoplasm: We then identified a cocktail of five peptides, including the three ppCT leader sequence-derived peptides (ppCT1–15, pCT9–17 and ppCT16–25), ppCT50–59 and ppCT86–100, able to induce strong CD8+ T cell responses in a majority of patient PBMCs, as monitored by IFN-γ production (Fig. 4c) and killing of IGR-Heu and IGR-Heu-TAP tumour cells (Fig. 4d).