We observed that mHFD feeding rescued the obesity-associated phenotype of OGT FKO mice, including the body weight (Fig. 4d), fat mass (Supplementary Figure 21), energy intake (Fig. 4e), and contents of palmitate (C16:0) and oleate (C18:1) in DAG (Fig. 4f and Supplementary Figure 22). The gene discussed is OGT; the disease is obesity due to melanocortin 4 receptor deficiency.