CSH2 and pituitary tumor: This finding is not only consistent with reports that implicate γ aminobutyric acid (GABA, a neuroactive ligand) in pituitary tumors (End et al., 2005), but it also provides additional support to our lncRNA-mRNA co-expression network: five of the nine mRNAs are part of the co-expression network, and all five of them (GH1, CSH2, GHRHR, SH1, GH2) are disconnected from the majority of the co-expression network (Fig. 4, left), and are instead, part of a discrete ‘satellite’ co-expression network (Fig. 4, top right corner).