Similar to classical oncogenes or tumor-suppressor genes such as eIF4F (eukaryotic translation initiation factor 4F, Bhat et al., 2015) and DLK1 (Delta-like 1 homolog, Kawakami et al., 2006), lncRNAs may act as oncogenes or tumor-suppressor genes by altering gene expression (Zhou et al., 2012; Kim et al., 2013). This evidence concerns the gene DLK1 and neoplasm.