Expression of the same three genes was confirmed by qRT-PCR in iPSC-derived dopamine neurons generated from the original GBA3 iPSC line, two further iPSC lines from the GBA3 patient, the three controls, the two other original GBA patients, and an additional fourth PD GBA-N370S patient (GBA4; Figure 2E). This evidence concerns the gene GBA3 and Parkinson disease.