For the treatment of ischemic stroke, Intravenous (IV) tissue plasminogen activator (IV tPA) is the only evidence-based therapeutic option for acute ischemic stroke patients and this has been the case since the 1990s [5], although intra-arterial thrombolysis (IAT) is a relatively safe and efficient short-term treatment for ischemic stroke which onset within 4.5 h [6]. Here, PLAT is linked to ischemic stroke.