Accordingly, those with serum PGI/II ratio of ≤3.0 had higher levels of tumor LGR5 expression (3.9 ± 1.1), as compared to those above 3.0 (3.3 ± 1.0), which did not reach statistical significance (p = 0.095, Table 3). This evidence concerns the gene LGR5 and neoplasm.