TYRO3 and colorectal cancer: Similarly, HCT-116 colorectal cancer cells expressing siTYRO3 were more sensitive to treatment with 5-fluorouracil [35,36] and induction of apoptosis in response to 5-fluorouracil, paclitaxel, or oxaliplatin was significantly increased in cultures treated with an anti-TYRO3 antibody [35].