In this regard, among the activating receptors expressed by NK cells, NKG2D, DNAM-1 (CD226) and NKp30 are emerging as key receptors for the recognition of MM cells, being engaged by their ligands expressed by tumor cells [5,6,7] and thus triggering NK cell cytotoxicity [5,7,8]. The gene discussed is KLRK1; the disease is Miyoshi myopathy.