CXCL10 and infection: Since MIG and IP-10 were among the most highly upregulated chemokines in the lungs of C57BL/6 mice, which were able to more effectively control B. pseudomallei infection, it is possible that both chemokines were important in promoting early clearance of bacteria in addition to any roles they may have later during infection in the spleens of BALB/c mice.