STING can sense bacterial signalling molecules such as cyclic di‐GMP and cyclic di‐AMP.60, 61 Like cGAMP, these cyclic dinucleotides can bind and activate STING and induce the production of type I interferons, which has been observed, for example, during infection with Mycobacterium tuberculosis and Listeria monocytogenes. The gene discussed is STING1; the disease is infection.