Mounting evidence shows that lncRNAs can regulate glucose metabolism in cancer cells in different ways, such as by directly regulating glycolytic enzymes (i.e. pyruvate carboxylase, fructose‐2,6‐bisphosphatase, 6‐phosphogluconate, phosphoenolpyruvate carboxykinase) and glucose transporters (GLUTs), or by indirectly modulating the signalling pathways (Wnt/Snail, STAT and p53 pathways and HIF, PI3K/AKT/mTOR and LKB1‐AMPK pathways) (Fan et al., 2017). This evidence concerns the gene AKT1 and cancer.