We found that, in a previous study, exogenous Cit alleviated the release of proinflammatory cytokines (TNF-α, IL-1β, and IL-6) in early sepsis and increased the release of late-stage anti-inflammatory cytokines (IL-4 and IL-10) to alleviate the inflammatory response of septic rats [4]. This evidence concerns the gene IL4 and Sepsis.