BCL6 and diffuse large B-cell lymphoma: A closer examination of the genes located in the patient-interacting regions revealed that the first viewpoint (Fig. 5, magenta shaded region) lies directly at the BCL6 gene, a transcription factor known to be affected in DLBCL, while the interacting region on chromosome 14q32 lies at the immunoglobulin heavy-chain (IGH) locus (Fig. 5d, e), suggesting a t(3;14)(q27;q32) reciprocal translocation.