OIP5 and central nervous system cancer: To investigate the regulation of OIP5-AS1 and miR-410 on the growth of glioma, we chose U87 glioma cells for transfection in vitro. We found that silencing OIP5-AS1 using siRNAs in U87 glioma cells inhibited cell growth via effectively suppressing proliferation, invasion and migration capabilities, and promoting apoptosis, as well as inducing G0/G1 phase cell cycle arrest.