CD4 and myeloid sarcoma: For example, Liu et al. [67] reported downregulated expression of miR-15b in CD4+ T cells obtained from patients with MS and mice with EAE, and demonstrated a consequent inhibition of Th17 differentiation through targeting of O-linked N-acetylglucosamine transferase (OGT), with subsequent effects on the transcriptional regulation of RORγt through O-GlcNAcylation of NF-κB.