We consider OLP to be a model of nonspecific inflammation due to the following pathological and micrographic features: (1) liquefaction and degeneration of basal epithelial cells and band infiltration of superficial lymphocytes in the lamina propria [27]; (2) inflammatory cytokines, such as TNF-α, and MMPs that potentially cause a disordered arrangement of epithelial basal cells and the fracture of junctions between the stratum basale and basement membrane [28]; and (3) an increased number of Langerhans cells and mast cells in OLP lesions [29]. The gene discussed is TNF; the disease is oral lichen planus.