The TNF receptor family is involved in many of the selected inflammatory diseases, e.g., TNFRSF10B in Osteoporosis, Osteomyelitis and periodontitis, TNFRSF11B and TNFSF13B in Osteopetrosis and Periodontitis, and TNFIP6/8 in Osteomyelitis. This evidence concerns the gene TNFRSF10B and osteopetrosis.