We performed RNA sequencing of tumor organoids from ApcΔ716Trp53+/+, ApcΔ716Trp53Null, and ApcΔ716Trp53R270H/R270H mice (Trp53 genotypes are different) and found ~350 genes that are specifically upregulated in p53 R270H-expressing tumors (Nakayama et al., 2017). This evidence concerns the gene TP53 and neoplasm.