For example, mutant p53 protein drives invasiveness and the scattered migration of cancer cells by promoting Rub coupling protein (RCP)-recycling of integrin and the receptor for hepatocyte growth factor (HGF), MET, thereby resulting in the activation of EGFR/integrin and HGF signaling, respectively (Muller et al., 2009, 2013). The gene discussed is HGF; the disease is cancer.