The diagnosis in the remaining patients were thyroid hormone receptor-beta mutation in 22 (4.4%), subacute thyroiditis in four (0.8%), toxic nodular goiter in four (0.8%), neonatal GD in three (0.6%), papillary thyroid carcinoma in two (0.4%) and 18 patients (3.6%) who were not assigned a specific diagnosis. The gene discussed is THRB; the disease is subacute thyroiditis.