To characterize the age‐related tau phosphorylation in female 3xTg‐AD mice, we immunostained sections from 2‐, 6‐, 12‐, and 20‐month‐old mice (n = 6/age group) with antibodies that recognize tau phosphorylated at Ser422 (pS422), Ser202/Thr205 (AT8), and Thr212/Ser214 (AT100). Here, MAPT is linked to Alzheimer disease.