Consistent with our RNA‐sequencing data, young and HP Cent T cells had reduced expression of both BAX, a key protein involved in p53‐mediated apoptosis (Reyna et al., 2017), and PD‐1, a cell death inducer also involved in cancer and autoimmune diseases (Wang, Sun, Wright, Wang, & Gu, 2016) (Figure 5b,c). This evidence concerns the gene TP53 and cancer.