While showing no effect on C/EBPα p30-WDR5 protein-protein interaction, OICR-9429 disrupts MLL/WDR5 complex formation, selectively upregulates myeloid-specific transcripts, suppresses proliferation and induces differentiation in C/EBPα p30 mutant human acute myeloid leukemia cells (Table 2) (54). The gene discussed is WDR5; the disease is acute myeloid leukemia.