As shown in Figure S2, the comparison of cytokine production in healthy controls vs. TKI-treated CML patients shows that the expression of IFN-γ by unstimulated NK cells is higher in middle-aged TKI-treated CML patients and lower in elderly patients compared with their age-matched controls, whereas the expression of IL-10 is higher in TKI-treated CML patients from both age groups compared with their respective controls. The gene discussed is IL10; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.