Furthermore, the transcriptomic changes of infected nasal epithelial cells revealed differential regulation of all 11 targets (CD38, HERC5, HERC6, IFI6, IFIH1, LGALS3BP, LY6E, MX1, PARP12, RTP4, and ZBP1) previously thought to be influenza-specific signatures (Andres-Terre et al., 2015). The gene discussed is HERC5; the disease is influenza.